A fight broke out among the heroes for possession of the box and was only ended when John Constantine took the box, being the only one capable of doing so without being corrupted. Zatanna and Constantine took the box to the temple of Hephaestus, where the three Justice Leagues had converged again. After yet another battle between heroes, the box went dormant and the Justice Leagues discovered a Kryptonite sliver in Superman’s nervous system, placed there by the Atomica, a traitor working for the Outsider, leader of the Secret Society. Then, the Outsider used the box to open a path across universes, allowing the Crime Syndicate to enter the Justice Leagues' world.
Since her attack on Veronica Cale, Cheetah had been captured by Cale and held in the basement of Empire Industries, where she was being experimented on by Doctor Poison. Cheetah suddenly dropped into a coma, before waking and massacring Empire Industries' staff, while screaming about the return of the so-called 'Dark Gods'. She attempted to kill Cale once again, but was restrained due to the timely intervention of Wonder Woman. Steve Trevor informed Diana that all over the world, people had begun acting strangely and warning of the Dark Gods. As she flew through the skies of Washington, she was suddenly attacked by a deranged Supergirl. After a lengthy battle, Wonder Woman was able to defeat Kara and restrained her in the Lasso of Truth, which knocked her unconscious. Jason returned after learning from the Fates that the armor that had been gifted to him by the gods was originally created for Diana, but had been mistakenly given to Jason after Zeus' death. It also allowed Jason to channel the power of any member of the Greek Pantheon, though he could only use one god's powers at a time. Jason began to explain his discoveries to Diana, but they were interrupted by a group of giant monoliths appearing in the sky, which began to activate. As soon as the siblings began to investigate, Wonder Woman was taken by a pair of Star Sapphires who needed her assistance due to an emergency on Zamaron. As Diana was forcefully teleported, Jason was left alone before the activating monoliths.
When last we left Wonder Woman #49, the battle brewing ever since DC's METAL cracked open the Multiverse seemed to be reaching its climax. With the Dark Gods playing similar roles to the Greek pantheon, but with all-powerful demands, enslaving humanity, Diana and her twin brother Jason were splitting up to oppose them around the globe. Just as they seemed to knock back their leader, King Best, the Dark Gods launch an assault on Jason.