Various Wonder Woman enemies would debut in the comic series. Issue #1 introduced Wonder Woman's nemesis, Ares, as the embodiment of all abnormal emotions, evil, and essentially all that Wonder Woman was against. Issue #5, the character of Doctor Psycho, a murderous psychopath with an intense hatred of women, was debuted, Issue #6 introduced Cheetah while issue #9 introduced Giganta. Also Issue #9 debuted Queen Clea, which would later help form the female supervillain team, Villainy Inc.. Later on Issue #49 debuted another recurring enemy, Circe.
In one episode, a newspaper editor named Brown, desperate to discover Wonder Woman’s past, assigns a team of reporters to chase her down; she easily escapes them. Brown, gone half mad, is committed to a hospital. Wonder Woman disguises herself as a nurse and brings him a scroll. “This parchment seems to be the history of that girl you call ‘Wonder Woman’!” she tells him. “A strange, veiled woman left it with me.” Brown leaps out of bed and races back to the city desk, where he cries out, parchment in hand, “Stop the presses! I’ve got the history of Wonder Woman!” But Wonder Woman’s secret history isn’t written on parchment. Instead, it lies buried in boxes and cabinets and drawers, in thousands of documents, housed in libraries, archives and collections spread all over the United States, including the private papers of creator Marston—papers that, before I saw them, had never before been seen by anyone outside of Marston’s family.