Various Wonder Woman enemies would debut in the comic series. Issue #1 introduced Wonder Woman's nemesis, Ares, as the embodiment of all abnormal emotions, evil, and essentially all that Wonder Woman was against. Issue #5, the character of Doctor Psycho, a murderous psychopath with an intense hatred of women, was debuted, Issue #6 introduced Cheetah while issue #9 introduced Giganta. Also Issue #9 debuted Queen Clea, which would later help form the female supervillain team, Villainy Inc.. Later on Issue #49 debuted another recurring enemy, Circe.
During the fight, Steve approaches Diana who can't hear him speak due to an explosion temporarily rupturing her eardrums. Steve, after much talking, departs and leaves Diana with his watch before boarding the plane which is taking off with the mustard gas. Ares eventually restrains Diana, imploring her to surrender and realize the futility of their fight. Diana notices the plane in the sky as she's pinned to the ground and watches in horror as it explodes with Steve sacrificing himself to save billions of lives.
Later, Diana, Zola and Hera had lunch while they were watched by Hermes. Orion, believing Hermes had bad intentions, attacked him before being stopped by Wonder Woman, and at the same time Strife appeared. Back at the apartment, Strife gave War's helmet to Diana, even though Diana still felt uncomfortable at becoming the new Goddess of War. In that moment, Siracca entered the apartment and told Diana that Milan had been captured by Cassandra. Wonder Woman asked Hermes to take her to Chernobyl, and he accepted to help.
In February 1941, Marston submitted a draft of his first script, explaining the “under-meaning” of Wonder Woman’s Amazonian origins in ancient Greece, where men had kept women in chains, until they broke free and escaped. “The NEW WOMEN thus freed and strengthened by supporting themselves (on Paradise Island) developed enormous physical and mental power.” His comic, he said, was meant to chronicle “a great movement now under way—the growth in the power of women.”
Years later, their deceit was discovered by Hippolyta. Angry at Antiope for defying her decision, Hippolyta sent Diana back to her room so that she could speak to her sister alone. Antiope reasoned with the Queen, reminding her that Ares was alive and would come for Diana some day. Hippolyta accepted this with some difficulty, and ordered Antiope to train Diana harder than any Amazon before her, until she was better than even Antiope herself, the Amazons' fiercest warrior. Thus, with the blessing of her mother, Diana formally began extensive training in all forms of Amazonian combat. Over the years, she became a formidable warrior.
The last issue of Wonder Woman saw very little of the Amazon. Instead, we watched her brother, Jason, launch an attack against the Dark Gods. He first tries to take on the Gods, named Karnell, Savage Fire, the Mob God, and the God with No Name. They quickly defeat him, but Jason gets the backup of Supergirl and the Justice League for round 2. The Dark Gods, however, aren’t pushovers and promptly defeat the heroes thanks to their leader, King Best. Before all seems lost, Diana returns just as King Best takes form and begins his path of destruction. Will Wonder Woman and Jason be able to contain this madness?
Wonder Woman (vol. 1) #179 (Nov. 1969) showed Wonder Woman giving up her powers and returning her costume and title to her mother, in order to continue staying in Man's World. The reason behind this was that all the Amazons were shifting to another dimension, but Diana was unable to accompany them as she needed to stay behind to help Steve, who had been wrongly convicted. Thus, she no longer held the title of Wonder Woman and after meeting and training under a blind martial arts mentor I-Ching, Diana resumed crime fighting as the powerless Diana Prince. She ran a mod-boutique as a business and dressed in a series of jumpsuits while fighting crime. During this period, Samuel R. Delany took over scripting duties with issue #202. Delany was initially supposed to write a six-issue story arc, which would culminate in a battle over an abortion clinic, but Delany was removed reportedly due to criticism from Gloria Steinem, who, not knowing the content of the issues Delany was writing, was upset that Wonder Woman had lost her powers and was no longer wearing her traditional costume.
Wonder Woman and the other heroes were finally released from the Firestorm Matrix when Batman used the Lasso of Truth on Firestorm. Superman was still infected with the Kryptonite shard inside his nervous system, but Lex Luthor was able to extract it, saving Superman's life. Luthor also assembled a group of villains that defeated the Crime Syndicate. Later, at the Batcave, Wonder Woman and the Justice League talked about the enemy that destroyed the Crime Syndicate's world and came to the conclusion that Darkseid would return.