Straczynski's run focused on an alternate timeline created by the Gods where Paradise Island was destroyed leading to many Amazons being raised in the outside world. It revolves around Wonder Woman's attempts to restore the normal timeline despite the fact that she does not remember it properly. Wonder Woman in this alternative timeline has been raised in New York City as an orphan and is coming into her powers. She is aware of the presence of Amazons, but does not remember her childhood on Paradise Island. Wonder Woman wore a new costume designed by DC Comics co-publisher Jim Lee. Writer Phil Hester continued the storyline.
Wonder Woman and the other heroes were finally released from the Firestorm Matrix when Batman used the Lasso of Truth on Firestorm. Superman was still infected with the Kryptonite shard inside his nervous system, but Lex Luthor was able to extract it, saving Superman's life. Luthor also assembled a group of villains that defeated the Crime Syndicate. Later, at the Batcave, Wonder Woman and the Justice League talked about the enemy that destroyed the Crime Syndicate's world and came to the conclusion that Darkseid would return.