Wonder Woman returns in Injustice 2 as a playable character. She is voiced by the same voice actress whom had voiced her before, Susan Eisenberg. Just like the previous game, she sides with the regime. Later when Supergirl landed on earth, she mentored her. later, her Supergirl Tried to free Superman from his prison, but were stop by Blue Beetle and Firestorm. Because he needed help to fight Brainiac, Batman decide to free Superman himself. When Brainiac invaded the earth, she was among many whom were fighting against his army.
Diana is depicted as a masterful athlete, acrobat, fighter and strategist, trained and experienced in many ancient and modern forms of armed and unarmed combat, including exclusive Amazonian martial arts. With her godlike abilities of incalculable superhuman strength, nigh-invulnerability, speed, flight, healing factor and semi-immortality, Diana’s fighting prowess is enhanced. In some versions, her mother trained her, as Wonder Girl, for a future career as Wonder Woman. From the beginning, she is portrayed as highly skilled in using her Amazon bracelets to stop bullets and in wielding her golden lasso. Batman once called her the "best melee fighter in the world". The modern version of the character is known to use lethal force when she deems it necessary. In the New 52 continuity, her superior combat skills are the result of her Amazon training, as well as receiving further training from Ares, the God of War, himself, since as early as her childhood. The Golden Age Wonder Woman also had knowledge in psychology, as did her Amazon sisters.
The chief chemist associated with General Ludendorff who specializes in chemistry and poisons. On her role, Anaya said, "Well, it was a small role in this big ensemble, but it is an important character in the story. I'm going to be a big nightmare" for Wonder Woman and Steve Trevor. Describing her character, Anaya said, "Dr. Maru loves rage and enjoys people's pain. She's creating terrible weapons, and her purpose in life is to kill as many people as possible, and provoke as much pain as possible". She researched World War I and Fritz Haber, the scientist who created mustard gas, to prepare for the role. On the character's facial scars, Anaya stated, "I went to Patty Jenkins and asked, 'What happened to her?' And she said, 'She did it on purpose.' I was like, 'What? Patty, you're going further than I ever imagined.' She said, 'She wants to provoke painful suffering, so she tested her own gas on her own face. She wanted to know how deep this form of her gas would go, so she put it on her own face.' You can see half of her face is completely gone. This is the sadistic side of Dr. Maru". She also stated her character "is quite the opposite to the lead role of this movie, one of the strongest characters ever of DC comics, Wonder Woman. I can tell you that Doctor Poison is someone with a capacity to provoke so much pain." On Dr. Maru's relationship with General Ludendorff, Anaya said, "I think that they have a relationship based on loyalty. Ludendorff is a very tormented General that lacks self-confidence. That's why, in part, he takes these drugs that Dr. Poison gives him. They are from different worlds, but they complement each other".
The Diana Prince alias also played an important role after the events of Infinite Crisis. Wonder Woman was broadcast worldwide killing a villain named Maxwell Lord, as he was mind controlling Superman into killing Batman. When Wonder Woman caught him in her lasso, demanding to know how to stop Superman, Maxwell revealed that the only way to stop him was to kill Lord, so as a last resort Diana snapped his neck. To recover from the trauma of killing another person, the Amazon went into a self-imposed exile for one year. On her return to public life, Diana realized that her life as a full-time celebrity superhero and ambassador had kept her removed from humanity. Because of this she assumed the persona of Diana Prince and became an agent at the Department of Metahuman Affairs. During a later battle with the witch Circe, a spell was placed on Diana leaving her powerless when not in the guise of Wonder Woman.