Wonder Woman returns in Injustice 2 as a playable character. She is voiced by the same voice actress whom had voiced her before, Susan Eisenberg. Just like the previous game, she sides with the regime. Later when Supergirl landed on earth, she mentored her. later, her Supergirl Tried to free Superman from his prison, but were stop by Blue Beetle and Firestorm. Because he needed help to fight Brainiac, Batman decide to free Superman himself. When Brainiac invaded the earth, she was among many whom were fighting against his army.
She also had an array of mental and psychic abilities, as corresponding to Marston's interest in parapsychology and metaphysics. Such an array included ESP, astral projection, telepathy (with or without the Mental Radio), mental control over the electricity in her body, the Amazonian ability to turn brain energy into muscle power, etc. Wonder Woman first became immune to electric shocks after having her spirit stripped from her atoms by Dr. Psycho's Electro Atomizer; it was also discovered that she was unable to send a mental radio message without her body.
Wonder Woman and the other heroes were finally released from the Firestorm Matrix when Batman used the Lasso of Truth on Firestorm. Superman was still infected with the Kryptonite shard inside his nervous system, but Lex Luthor was able to extract it, saving Superman's life. Luthor also assembled a group of villains that defeated the Crime Syndicate. Later, at the Batcave, Wonder Woman and the Justice League talked about the enemy that destroyed the Crime Syndicate's world and came to the conclusion that Darkseid would return.