John Byrne's run included a period in which Diana's mother Hippolyta served as Wonder Woman, having traveled back to the 1940s, while Diana ascended to Mount Olympus as the Goddess of Truth after being killed in issue #124. In addition, Wonder Woman's Amazon ally Nubia was re-introduced as Nu'Bia, scripted by a different author. Byrne posited that Hippolyta had been the Golden Age Wonder Woman. Byrne restored the series' status quo in his last issue.
Preparing to get Zola back from Hades, Wonder Woman and her male companions sought out Eros in Italy. She hoped that he could lead them to Hephaestus, who might have been able to arm them appropriately for battle with the ruler of Hell. He lead them to Mount Etna, where the blacksmith agreed to arm them. As retribution for his aid, though, Hades sent a monster to kill them all, which had to be dispatched by Diana. Afterwards, Hephaestus armed Diana with new weapons, insisting that she take Eros' guns of love with her to Hell.
At the end of Infinite Crisis, Wonder Woman temporarily retires from her costumed identity. Diana, once again using the alias Diana Prince, joins the Department of Metahuman Affairs. Donna Troy becomes the new Wonder Woman and is captured by Diana's enemies. Diana then goes on a mission to rescue her sister, battling Circe and Hercules. Diana defeats the villains, freeing Donna and takes up the role of Wonder Woman again. Circe places a spell on Diana, which renders Diana into a normal, powerless human being when in the role of Diana Prince; her powers come to her only when she is in the role of Wonder Woman.
The Diana Prince alias also played an important role after the events of Infinite Crisis. Wonder Woman was broadcast worldwide killing a villain named Maxwell Lord, as he was mind controlling Superman into killing Batman. When Wonder Woman caught him in her lasso, demanding to know how to stop Superman, Maxwell revealed that the only way to stop him was to kill Lord, so as a last resort Diana snapped his neck. To recover from the trauma of killing another person, the Amazon went into a self-imposed exile for one year. On her return to public life, Diana realized that her life as a full-time celebrity superhero and ambassador had kept her removed from humanity. Because of this she assumed the persona of Diana Prince and became an agent at the Department of Metahuman Affairs. During a later battle with the witch Circe, a spell was placed on Diana leaving her powerless when not in the guise of Wonder Woman.